Freely modify and utilize proteins.
Keywords: in vitro protein synthesis, enzymes, membrane receptors, membrane transporters, transcription factors, protein engineering, biomolecular engineering
Many proteins in living organisms need to adopt precise structures to function as high-performance nanomachines. In vitro protein synthesis systems are an excellent technology for producing high-performance proteins. For example, animal proteins can be produced in vitro without killing the animals. Even in the case of infectious microorganisms and viruses that are dangerous to handle directly, as long as the DNA sequence information is available, it is possible to produce the desired protein in a safe environment. Currently, research is focused on membrane proteins and enzyme proteins, which are considered difficult to study in terms of their functions. Many membrane proteins are also drug targets, making them important for pharmaceutical and pesticide research. Additionally, many of them play crucial roles in controlling the transport of nutrients and metabolites into and out of cells as membrane transporters, and elucidating these functions has significant academic value. Enzyme proteins are ideal catalysts that can efficiently produce compounds found in nature at room temperature and pressure. By improving them in vitro, that is, through molecular evolution, it is also possible to create enzymes with more advanced functions.
- Company：埼玉大学 オープンイノベーションセンター
- Price：Other
